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pentobarbital will lower the extent or impact of prednisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will decrease the extent or influence of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Powerful or moderate CYP3A4 inducers may well raise rate of